Leighton Meester’s Early TV Days Resurface: Fans Obsess Over Her 2006 ‘House M.D.’ Appearance

Social media is suddenly filled with resurfaced pictures of Leighton Meester from her 2006 guest appearance on House M.D., long before she made a big difference as Blair Waldorf in Gossip Girl. The fans are freaking out over her cute girl looks and acting skills. They have been reminiscing about the really early television drama featuring Leighton Meester.

The photos have gone into borderline discussions on Instagram, Reddit, and Twitter, proving that nearly two decades later, the charm in Meester is still timeless.

blonde leighton meester in ‘house m.d’ 2006 ✩ pic.twitter.com/ecpVU0jGJw

— ❦ (@saintdoII) November 5, 2023

Leighton Meester as Ali in House M.D. (2006)

In 2006, Meester guest-starred in House M.D. Season 2, Episode 14, titled “Sex Kills.” She played Ali, a teenage girl suffering from a medical condition that led to her developing an inappropriate crush on Dr. Gregory House, played by Hugh Laurie. Her character’s flirty and slightly eerie behavior added a layer of intrigue to the episode, making it one of the more memorable guest appearances in the series.

This was one of Meester’s early acting gigs, long before she landed her breakout role as Blair Waldorf on Gossip Girl in 2007. At the time, she was still carving her path in Hollywood, appearing in various TV shows such as Veronica Mars, 8 Simple Rules, and Entourage.

Fans React: “She’s Such a Pretty Blonde”

The resurfaced images of Meester from House M.D. have drawn thousands of nostalgic and adoring comments from fans across social media. Many are taken aback by how different she looked as a blonde, while others are simply excited to relive this moment from her early career.

• “She’s such a pretty blonde.”
• “Leighton was so hot in this episode of House.”
• “I die for her. I followed Dr. House only because she was an extra in two episodes, and now she’s trending again after these pictures.”
• “This episode was freaky as hell.”
• “She’s so pretty. I used to have a big crush on her.”

The nostalgia is particularly strong for fans who watched Gossip Girl religiously in the late 2000s and early 2010s. Seeing Meester in a completely different role and aesthetic has reminded many of just how versatile she was before she became the queen of the Upper East Side.

From House to Gossip Girl: A Star on the Rise

Meester’s guest role on House M.D. was just one of many stepping stones that led to her rise in Hollywood. Just a year later, she would land the role of Blair Waldorf, the quick-witted, stylish, and cunning socialite on Gossip Girl.

Her performance as Blair became legendary, with many considering her the heart and soul of the show. Over the years, she has continued to work in both television and film, starring in Single Parents, The Roommate, Country Strong, and The Weekend Away.

However, moments like this—when an old role suddenly goes viral—remind fans of just how far she has come in her career.

Why Fans Love These Throwback Moments

There’s something special about rediscovering an actor’s early work, especially when they later become famous for an iconic role. Seeing Leighton Meester in House M.D. before she was Blair Waldorf adds an element of nostalgia and appreciation for her journey.

As these photos continue circulating online, one thing is clear—whether blonde or brunette, whether a lovesick teen in House M.D. or a queen bee in Gossip Girl, Leighton Meester has always had an undeniable screen presence.

What’s next? Fans will surely be keeping an eye out for any more resurfaced gems from her past.